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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6fd8774197b4e95fb933655f7d144f31ba105be07bfbe3db1c23b18c901cdbf' 
  AND token = 'eDJMkEh7RT9AzQA+bAr3WOjtTPbbDvFzpywe/lnPa/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}