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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1655d3287acf8605a19a5cc5787cb389d7cb4701d868d9267b66f43a4c2c4a22' 
  AND token = 'WFWppuzARCkdE6xYvwjlEu/vKNTh3f0103Qj9T7rdA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}