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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a62dceb78d9a2bb645259a3e4c981f589d674470320a56f08d943ceedd6346' 
  AND token = 'JtxmP49qNFnM7yb9Ijs+72QVgrA4OHcT/G/clrp9Ifw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}