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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc7cc1a6601fc78e7496ccedf4e599ac5f4442cdcc9018c672eb291fb81a516' 
  AND token = 'FcXf/w6qnbOQAkkHrQwmDKv1E4JW2fQ398u1j3Imoy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}