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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7949273ec2f3ebf21c75a36c26f91ea8184062de18a06dfae23d65c35b6d0b9' 
  AND token = 'O84Gw3OvEO5nd+cLpsdSqkl7NE2vLdGCZ3szkH4sSeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}