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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efe19deecff384dd86f9e4e2bf1ae64af66d1695cdac8cc3bb786afaaf9527f' 
  AND token = 'xJLFVEOOf1iAYiPK+1IPipnWue1IHrLRurhN3FNQk10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}