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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1baa08ce69cf4b1f1fd5148544b4d75c2b7a663efe46b5700b7b13d44ee333' 
  AND token = 'mXlAp395aHQnEJnY/5qtcbydqe0fTDN47vEmzQkMFuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}