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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654b0777d543900c6b9fd01aa5bb25a30052c9cb4399ccbb5b7bf6a2817ad10a' 
  AND token = 'ZP6yBIauxzSrfwmeOBdW5gTYIp6zDXADvzAp24bEbO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}