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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5275d51067c7310a56d46de5003a67f78d01ca182bbb5ebfa977eae2fc9da010' 
  AND token = 'K+YjMfNb+euauOc4pL2E4tQsGK5ArMSM8h64MzsfZ7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}