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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0e8e9e3cbb4d92db742f56f2016f67d26c781f513eeec334a2541f5216da57' 
  AND token = '3ooOBadAZk98wHnziC2V4JlZI8idS/fGtWLEEl5C7nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}