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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74704752d35c9ae1953b91757f7b2c2126c5aa7a4506064fc6b6ff6f9654b099' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}