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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed3ec3f026910ae3ec5ad7880bdfb299bd26f2d3453b4b11c3ac05e18088106' 
  AND token = '503lILhSL+1xbkOxgzHth22QXsK0JDRi5k0BLspGqOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}