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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c74d584f9612fccc315e64a8a0c762d9da8afc8b52c4d52d717efee13e664af' 
  AND token = '/apf2Yag3iCtHLjMEPYJwNpb7Pa7qBeCSIZ6lEEUllY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}