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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500e47fbfd88bc08a65d2cc7c446af66f42688fda3a7c6f6a694a3cf5632c5ac' 
  AND token = '2XkuiCQNNyndr12QgknUAS1UrVxmDFoB1YLJOX4UGhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}