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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16c3499010ef9977822e4f278a5d9aa881860cef00864ee6ea34f0f41a86489' 
  AND token = 'JRmc24GNOVL/JLzI8q4JPafe99RDWO8YDV2jlyKvefU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}