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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e408d7da41f007a334eb7190d3c06f88f251df1812a5e117ebbb832fa80bb9ff' 
  AND token = 'yLJSs3LnBNPgj++skgmbsuCAMizrdyUHsYr+2O4PbiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}