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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a880ce1a1c8a7cb2b7afbc79b153d799e168590cbc846b42f7fb612be735ea96' 
  AND token = 'ZgVXIAmxyzJAXlcufvgeqUporW6iSBeo01Tl/wq7+0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}