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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a010a0b02e25c57caa873613b2c7c592ad83a7b825e9dbab5c4407859b06c44' 
  AND token = 'Nj20sh98lTVXYlzEWBV5PH9wt4mwn3FHoqrFzGX4dy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}