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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5aca8d264b99631bd3d2fce3b759d63fe4ae727180ef62ff68b71160a9f80c' 
  AND token = 'JydtTLlps9eM3ha0TchHR0+qBAZrVzBrMPu5QrMp92A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}