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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c221945ab823b1d3300a9d35ea6f961a387e54a0a011117600c7d49026c918d0' 
  AND token = 'Yret1GHeii+LFBHGi/jSsajbkwBYNYAdEnL5i9r3Pck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}