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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f9fb593478bd33e50adfafb6c481fc742acdc70f9a87c7b63c9864c25f5f44' 
  AND token = 'sr55+Su0pD/Tmhza4pA0VKBZOXgr4DqbPVLDe9pCfiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}