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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd603f18f9f0c262cd9888f84673a3f121f4b745e11b567f5171dfc7464fb574f' 
  AND token = 'g7EweXagrNZZUomgcnS+RahdTJAuw3mND39E86nQ318=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}