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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e1d7d122f18a4c238bc5861204d2facf178c7c5e984bf10a6ed09a0f424c14' 
  AND token = 'pSVusNrVWywYgjWttAohbrJuOCtFldxQg45hqd8Ieg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}