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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79965564783a2be0fd26b132f86921289d1ec49b01e84f90f0afb6c93a7cbb77' 
  AND token = 'ML9duu/DNo+ymSINNsjbaKBRZov8xIIZNlOnsLywr8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}