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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888593e3aa1c8982c1a2872324fff204de000c746e0361b840425c334a359178' 
  AND token = 'r7Ia8llVy9SBHAfDUYeg+v9blezsWiLMIfDAVjltw1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}