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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc62bb644758fdec80308bfeb06ceb6f3bbc50491006e12fb55517251063bd1' 
  AND token = 'ZQWh0wN+/TiNFWCq/h97hfjTW6IzOvmbwRY4QDRYKcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}