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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1392d8d0b53b289c613ca1c8bb7d2c8749ca64d4c8406d823753000383d611b8' 
  AND token = 'WxW1hah5lhfXXviLb3/5tGkZbx6+KugQNR3MecihV+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}