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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0651c02250d2197c0c1a7775e371b1ad3c2e71f3a08a990586b6da2817d31781' 
  AND token = 'az9TM7FbZI8OolSSUpf9mjRzXiVqqTEjLD8cSZrWyAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}