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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19e33139ac8586cd083dfeb0fcc14d678787133dd7d2013892db121f1b31627' 
  AND token = 'P7FBglBfjERrHsReo8kojCxeOOT+9HXTpVjHkKsOeso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}