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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4bd8dcd9a1d26fa9145b9017569981924ab27187b4512c65120a04dab3a71f7' 
  AND token = 'lF0H0M/wd+e+HI+rhSoiYxlKdF3HJ0j+pfi+mXzUIX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}