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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bbf0a73c911f2b275da700f45539c47ded7dfbe199d5cc288e200d0e125fd9c' 
  AND token = 'cGWrabqzAoW8Bc7/wVkQq56Q9v9jTRdydyRb1lDjXIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}