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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e972f18de1f8ca79a8a2f1bb60678503b0ba970fc8acc256c74e31e5141ea80' 
  AND token = '1wf2fCiZye55um2+1pTwu4KlgyRMY19XVdA552qI1D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}