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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc161c86a8e45a286377f7b0562430e87d1f671580555a4283047ee6d0ea6a2' 
  AND token = 'Ew/Ub5StIjBNIpRtyu89uYl6UsCrmDnxaqMJl6Z/gg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}