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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a138550ea9b17898169c685b8ec071dc531462f90a1c1a503f27f8a515e263f4' 
  AND token = 'Rc/umIJ3IH+hvl8MN4++wg6MTjtZ9mTnyR9E/tnE05k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}