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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fa7f0e2dcc4fce6ad3a592070ab9287a0c54c6332c9e3e2f5b965b095faa44' 
  AND token = 'fX3/qoq39EZWF7eLKYvd7ZlYErUFzccrs7QWXRDpgOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}