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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8488d4532caaafe697fa8705cb5b9ebb9c461efacb4565dcfb1f979e5c4b5d30' 
  AND token = 'TSXfR2dQ3gU8TvwfBj4yKCs04dYVjEKAbqZogEUjXXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}