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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd2b2c48511364aa60681f77240e8669e715f92a225f29a6041a5ac9ac3180b9' 
  AND token = 'BREcrcd73I/0jN+8qurywiAvxY5oehEJFvxhaDEozsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}