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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d39d22ddf751fd0dd57a013bbc10cb71669198935de1af879587a89c1e662a' 
  AND token = 'y+Sg51jgALFPBH6EsQ0CJxzefl6h5voaJ905Y4hP7IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}