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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4c4492b84b88a02f1eb855c94f505629f3df290477320fff985ec12a342d32' 
  AND token = 'Se7BVX2PT7Z3YcLJZtGr7/BTAyRKZWD2ibnWwXE0QQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}