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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce4bf55db7debb595cd27828d015c95207f3aa2dbc0372aedd149edd884d689' 
  AND token = '/Xq1D4csMLUc4oUvfEAFPwa0EMMvOh7IIlitaZ0hdwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}