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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78378464df1b7d7abca9614de3d06d7f701c56423437fb1d75dceb316d4d5be1' 
  AND token = 'bbFTJxPW4atrZPdNGYmlhphDNsvAVCzypjxxi9y/FHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}