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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f880004cfe05028d640cedf6f5df82307512d22991bf9194c0f26582b91aebc' 
  AND token = 'Nx2d5ETgE0wsDcYxpfzCzd1xFnqpY+bQTwtOkOUnCcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}