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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a6ba22ec0e50709a3d56db0c24a3705b190e5aa71e60b9ebeb994082f450de' 
  AND token = 'q4+7z6X1g8WbmcrnRCFmuzyU6Vv/ocP3ziKit9AFqOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}