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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de5aca5968dbd75dc24f9b7d7d3c1eb25317d0e7bdad9e42ae0df3d1a4d27f9' 
  AND token = 'RziBz5eACTo1OxlNCip0tBvm5YJeZtEY6x4t+baxirw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}