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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b808ac035a65686dd194ea43bf069cd27197bd47de8baaefa15111912fd75d1f' 
  AND token = 'mV46nAQvDe40vWTmAxjEAdD5n0t6RM1o1msMsSgVwfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}