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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e7c756238d463b8fe3288bdb1d7d0a87c4793d5da289927a365f1d44d0f927' 
  AND token = 'DTi5IgWJvNJc7B7rlxIiO0P8RTzIKw7zb2qtJREfbis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}