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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a4742d667c1855b7c517fe92f1e0c02421b9fda531a8c2bcc8ca35c45f77f65' 
  AND token = 'WWUi0/Ei1sB7RAD7V2oHNTUwUWEGBINBEI45gkF8bV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}