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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3c9330a9e8a94e173ff7b3564de209985709501d05392f1395d780a28d96ea' 
  AND token = 'G2fFNqnSibtAsfRsJ2a2LDSO3UdVtM2iNRYXbioA+38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}