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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ec478b70cd4dab3b4cbfa06e49556642f245c3520de666540c65a3332442f8' 
  AND token = 'Dshj5zmuRT8EvD2YcTYUzx5nw6XscWpT1UIYz5gdH3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}