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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd1d9526b5a3816201a25ef5fce310831be4077c51679dc2ca022a6fae263d2' 
  AND token = 'iQKyD2cJxpbGj73vQse5IOXqnzb6be38PilCi3XKxj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}